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How does itching form?

2025-10-21 20:14:33 Mother and baby

How does itching form?

Itching is a common physiological phenomenon that almost everyone experiences. Its formation mechanism is complex and involves the interaction of the skin, nervous system and immune system. This article will combine hot topics and hot content in the past 10 days, analyze the causes of itch from a scientific perspective, and provide relevant data and cases.

1. Physiological mechanism of itch

How does itching form?

Itch (medically known as "itch") is a feeling caused by stimulation of the skin or mucous membranes and transmitted to the brain through nerve signals. Its main formation mechanisms include:

typeTriggerRelated neurotransmitters
mechanical itchMosquito bites and frictionHistamine, 5-hydroxytryptamine
chemical itchAllergens (e.g. pollen, dust mites)prostaglandins, leukotrienes
Neurotic itchneurological diseaseSubstance P, calcitonin gene-related peptide

In the past 10 days, searches for "mosquito bites" and "allergens" have increased significantly, especially during the summer when mosquitoes are active and when pollen allergies are most common.

2. The relationship between recent hot topics and itch

The following are the topics related to itch that have been hotly discussed on the Internet in the past 10 days:

hot topicsTypes of associated itchDiscussion popularity (index)
“Tips for relieving itching from mosquito bites in summer”mechanical itch85,000
“How to relieve itching from pollen allergies”chemical itch72,000
“What to do about itchy skin with diabetes”Neurotic itch68,000

It can be seen from the data thatMosquito bites and pollen allergiesIt is currently the most concerned itch-related problem.

3. Treatment and prevention of itching

There are different treatments for different types of itch:

1.mechanical itch: For mosquito bites, use antihistamine ointment (such as hydrocortisone) or cold compress to relieve the bite.

2.chemical itch: In case of allergic reaction, avoid contact with allergens and take anti-allergic drugs (such as loratadine).

3.Neurotic itch: For example, itching caused by diabetes or herpes zoster needs to be treated according to the original disease, and neuromodulatory drugs should be used if necessary.

Recently, “natural ways to relieve itching” has become a popular search term, e.g.Aloe vera gel, peppermint oil, and baking soda solutionand other home remedies are in the spotlight.

4. Progress in scientific research on itch

Scientists recently discovered thatImmune cells (such as mast cells) and nerve fibersThe interaction is key to the persistence of the itch. Here are the latest research data:

research instituteDiscover contentPublication time
Harvard Medical SchoolDiscovery of new itch receptor "MRGPRX4"July 2023
University of TokyoUncovering the role of IL-31 in chronic itchJuly 2023

These studies provide directions for the development of new antipruritic drugs.

5. Summary

The formation of itch is the result of multiple factors, including external stimulation, immune response and nerve signaling. Recent hot topics show,Mosquito bites and allergiesIt is an itch-related issue that the public is most concerned about, and scientific research is constantly revealing its underlying mechanisms. In the future, with the advancement of medicine, more efficient anti-itch methods are expected to be available.

If you have persistent itching or other symptoms, it is recommended to seek medical treatment promptly to avoid delaying the condition.

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